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YOSHIDA Toyokazu
Title

Professor
Department Department of Chemistry and Biomolecular Science
Course Biomolecular Science Course

Research fields


For the purpose of applying enzyme reactions to produce usecul compounds, I am studying on the funcional analysis of novel microbial enzymes. In natural environment of earth, various and numerous microorganisms live universally and they possess unknown enzymes useful for us. For the syntheseis of pharmaceuticals and agrochemicals in an eonvionmentally friendly manner, enzymatic reactions can be utilized in the production systemes.

My object of study in the field of applied enzymology and microbiology is as follows: (1) Funcional characterization of novel decarboxylases catalyzing the reverse carobyxlation reaction and their application to the synthesis of useful carboxylic acid, (2) Eneyzmatic synthesis of optically active amines using novel enzymes such as imine reductatse, aminotransferase and hydrolase, (3) Application of nitrile-degrading enzymes to the industrial production of useful amides and carboxylic acids. In experiences of the above studies, the findings of novel microbial enzymes and genes are important to develope a new bioconversion system. Therefore, I have been continuing to isolate microorganisms extensively from soil samples.　

Fig. 1 Microorganisms isolated from soil samples

Research Overview

Research Keywords

Microbial Conversion

Enzyme Utilization

Enzyme Catalysis

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