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OH-HASHI Kentaro
Title

Associate Professor
Department Department of Chemistry and Biomolecular Science
Course Biomolecular Science Course

Research fields

As ER stress has been demonstrated to be associated with the onset and progression of several neurodegenerative disorders such as Alzheimer's and Parkinson's diseases, To understand the molecular mechanisms of these diseases, I have been characterzing the following factors.　　　　　　　

1. Transmembrane protein 132A (TMEM132A) which is highly expressed in neuronal tissues 2. Novel ER stress-inducible factors including CRELD2, MANF and Chac1　

Fig. 1 ER stress signaling pathways Fig. 2 Subcellular localization of wild-type CRELD2 in CO7 cells

Research Overview

Research Keywords

Neuronal Cell Death

Neurotrophic Factor

ER Stress

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